5 times

?? Once the cartridge is seated, the space between the lips and the film window is (generally) less than one frame. So one needs to advance and blank-fire once before being in business. If I load the cartridge in a darkroom, I lose
zero frame. Unless the cartridge felt lips are defective, as occurred to me recently --manufacturer made good for the loss. Say, you advance not one but two frames for peace of mind... but 5 frames!
To confirm take-up spool is properly engaged: after advancing one (or two) frames, rewind gently until you feel a moderate resistance.
The answer is just above.