know that's a very generic question, because preferences will differ from person to person, and the end justifies the means, but from a quality perspective what are the differences?
The digital vs film debate is over. Regarding image quality, in general, FF has better optic image qualty than film since around 10 years ago, but film MF today surpases in image quality any Pro digital camera, including digital back costinf $40k.
Beyond image quality, there are other concerns were digital or film are superior. Digital is neatly superior in low light situations, film is neatly superior in sunlight, specially for portraiture.
Films like Portra 160 are still conserving detail by +5 overexposure !!!
detail in the highlights is usually way more important than in the shadows because glare texture allows he mind to make an interpretation of the volumes.
Of course if the photographer doesn't know how to take advantage of highlight texture or the scene is dull then this is no advantage...
Another film strong point is that you have a
dedicated sprectral response for each situation, Velvia 50 and Portra 160 have each very different interpretations that are top-notch and special for their intended applications. Instead sensors are for general usage...
Canon sensors are slightly better for skin tones, while Nikon sensors are slightly better for the rest, this is from the RGB dyes on the pixels, you always can adjust in Ps, but each sensor have an slightly better potential for one thing or the other. In the film case there is no slight difference... Portra is a totally powerful tool for portraiture, blowing miles away anything digital if the photographer is a master of his tools, and a Velvia 50 8x10" slide blows anything else out of orbit for landscape... there is no fight or rivalry, they play in different divisions.
Of course today film is not much a Pro tool today, photography work is cheap, film is slow and counter productive, and expensive if you shot Pro a lot... and market won't value much the film nuances, people are used to Nose jobs made with the smatphone selfies...
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Then we have grain.
Grain is not only a technical defect !!! in the 1980s Kodak planned to discontinue Tri-X because TMax had less grain. Photographers rebelled and assembled a riot aganist Kodak and finally they gave up their plans. Today, some 4 decades later, Kodak still makes profits from that product !!!
Grain structure has an aesthetic impact that has its roots in the ancient photographic culture. Grain usage has evolved during a century and a half, films and photographer made a co-evolution, a bit like electric guitars and amplifiers, you don't want a perfect linear amplifier !!!
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Finally, you may want
authenticity, a grain in the film has received a photon that came from (perhaps) the sun an your subject reflected reaching the crystal you see developed, this may have no importance for some, but it sports a kind of purity that many artists value.
Recently Sally Mann made an exhibition with the most impressive prints many have ever seen on a wall. Basicly she departed from bare hand cut glass plates and simple chem, and never complained if a lens had an extensive crack in the middle... to end in those top notch silver prints (No AF... no zoom...), a great photograph may have many ingredients, but sometimes authenticity is the most powerful tool.