I always avoided traditional pyro due to its toxicity. Again, never liked staining developers. Back in the day all of the Zone system nerds were just gaga reviving the old "grails" that could also kill you. I do believe it is an exceptional choice for alternative process negatives that also print well on silver. I believe the newer formulations (PMK, HD) are not nearly as toxic. Honestly, I don't play with lots of developers; I try to use one and develop my process around it. D-76 was my developer when I was really shooting a lot, but I switched to HC-110 as a single shot. Works better for my workflow. I was playing a bit with X-Tol (least toxic) way back in the early nineties, but I was just too comfortable with D-76 and didn't need to "improve" the developer portion of my process. I needed better compositions! I moved my film exclusively to medium and large format; when you do that you usually have so much better tonal gradation and fine grain that you don't need to chase the small gains (again, for my preferences). When you shoot small formats, small gains mean a lot more. I will say, when I was a student at RIT in the early 90's, we learned to eke out every possible bit of tone and grain we could from those little 35mm negs!
PMK is toxic, Pyrocat HD much less so.... but stopped mixing PMK from powder and eventually switched to Pyrocat in liquid form