220 film lets you shoot twice the amount of frames without any kind of interruption that could be a detriment on your creative flow or process. With 6x4.5 format i get 30 shots (some backs can get 32) which is a lot, very close to a 35mm shooting experience.
Then, if you develop at home, you're developing twice the amount of film in only one operation, with only one spool, using only the same amount of chemicals. Yes you can do the same by taping two 120 rolls back to back, but it's a bit more effort (unwind two spools, tape them, etc).
Backing paper problems are lessened since the backing paper is used only at the beginning and end of the film.
220 film can be rewinded easily since the film is taped to the backing paper at the beginning AND at the end. Opening up more creative possibilities. Redscaling a C41 220 film should be very easy.
I love 220 film so much, i can't understand why it hasn't won over 120, considering that a lot of the pro medium format cameras are ready to take 220 film or have wide availability of 220 backs, like Mamiya C330/220, Pentax 6x7, some Rolleiflexes, Bronica ETR, SQ, GS, and others. I mean, 220 film was introduced in 1965, so many, many, many classic cameras have the capability to use 220.