I shouldn't have mentioned the Howtek. That was coincidental to my point. I was responding to your earlier post about best setting for V850. I found I was able to sharpen V850 scan of a 4x5 BW at 2400 better than 4800. I don't know why that is so.
Alan, many times we require several consecutive sharpening operations of different radius and % intensity. If you go this way you will get same good job independently of your dpi scanning.
In the Epson V850 the sensor outresolves the scanner's lens by a x2.2 factor if scanning 6400dpi, optimizing this may require a particular sharpening and %. But we do not only sharpen the scanning, we also may be sharpening the taking lens work, that requires a different radius and another %.
Consider this analogy. In a "perfect" digital image you apply a blur filter taking 2pix radius and 70% intensity. Later you apply another blur filter of (say) 7pix and 20% raidius. If you want to recover the image you will have to apply two consecutive sharpening actions, no single sharpening will work perfectly.
When optimizing an image sharpness you may have to perform more than one sharpening. In the case the scanner resolution matches the lens resolution then with a single sharpening you may get a good result.
So yes... you may obtain a better result from a single sharpening operation at some scanning dpi, but if you perform several cascaded sharpening operations you overcome overcome that problem and you perform always an smart job.
Additionally, you need more sharpening operations in the workflow, after you resize to the final size (from the larger edition size) you may sharpen again. And additionally you may make another sharpening that is calculated from the intended viewing distance, the print size and the pixel density in the print, this is to maximize acutance perceived by the eye while totally avoiding overshot.
Because of the cascaded operations required it's essential to work 16bits/ch, to not degradate the image.
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So the shorter answer is that the scanning work requires a radius for the sharpening and the taking lens work (+ film result) requires a different one. It can happen that depending on the scanning dpi a single sharpening works better because the required raidus match for both situations, but you can always cascade several sharpenings of different radius for a perfect job.
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If you want, send me the 2400 and 4800 original crops and the sharpened results, and I'll give you the sharpening operations at 4800 that matches or improves the 2400 workflow.