Specific craft and specific tools have always gone together. But you never know what it will be actually like until you are married. A person doesn't just use his gear - he gets moulded to it. It's just like that when taking a significant step into equipment you aren't familiar with already. There's a learning curve before you really understand the capabilities. And in my case, lest I get rusty, I make sure to periodically switch things up, and reacquaint myself with cameras and lenses which I might not have used for awhile. And that is also a great way to get the creative juices going again if some former approach has temporarily lost its spark.
Travel logistics, cost of use, commercial applications, etc are a somewhat different topic. But having a diverse arsenal to choose from is helpful. But I don't like to have too much in use at one time - that just gets complicated.
Old age logistics are one more element. I just loaded up my 8x10 gear in the pack. How come it feels heavier than last year?
But with Spring warmth arriving, there will be less risk of shoulder bursitis. If that starts acting up, it's back to 4x5 for awhile.