I have been lucky. I brush (paint brush, 1" to 1.5" wide) until the sensitizer is all gone, then a little more to get ride of any last liquid of the brush. I notice what looks like scratches on the tissue. but upon closer observation, they appear to be streaks of uneven swelling of the tissue. When I hang the tissue to dry, these lines disappear as the surface swelling and then drying (w/ fan) smooths out the surface of the tissue. While my scenes tend to be busy, which can hide a lot of sins, I have enough images with smooth tonality that I would see any scratches. Plus any surface defects get hidden -- in the final print using the single transfer, the surface of the tissue becomes the bottom of the image (next to the permanent support paper) due to the transfer.