One difference as the size of film is increased is depth of field and its effects. For example, maintaining sharp focus throughout a scene, one needs to use smaller apertures, which lengthens exposure. Movement can become more visible, perhaps blurring moving objects. This can effect the mood of a photograph.
Or vice versa, bokah becomes more pronounced if one is trying to stop action as they might with 35mm. (That is, to maintain the same shutter speed in MF compared to 35mm, may require larger apertures.