I still have mine, but since I got an Coolscan 8000ED for medium format scanning it doesn't see much use. In fact, in the last 2 years I've only used it to scan other people's APS film.
As far as I know, there are exactly zero supported SCSI cards for Windows 10, much less Windows 11. I was able to get an Adaptec Driver to work for a while, but I pulled the card a couple of years ago trying to solve what turned out to be an unrelated problem, yes, USB 1 is slow, but most of the time is still spent doing the scan itself. I can't speak to other scanning software -- once I bought Vuescan to address OS incompatibility I stopped looking.