Typically, the lower the ISO, the thinner the film, but some films are made extra thin for various reasons. One is to get more film in the camera/film cassette. Similarly, to make long rolls of film smaller in diameter & weight. Microfilm is very low ISO and very thin to be used in long rolls used in microfilm readers. Many submini camera users use microfilm to get more than the typical 12-20 exposures from their camera. For example, you can load a tiny Minox camera for 100 exposures using micro film -- it has to be "pulled" to lower the contrast, but the results are amazing.