I didn't like the 35mm plastic holders that came with my HP scanner even for full-frame use, and they were really bad for half-frame negs. When scanning transparencies, the scanner's (automatically set and not manually controllable) focus point is set a tiny fraction above the glass for a mounted slide. Getting negatives to that exact height isn't easy; just laying the negative strips right on the glass results in soft images.
I made a crude cardboard mask - just two thin pieces with a cutout for a five-frame strip (or nine half fames) sandwiched together with a piece of tape on one long side. The cut is just tall enough to mask the sprocket holes. It's not an ideal solution - with no cross-pieces, film curl is a problem, so I generally let my negatives flatten under weight for a couple of days before scanning. And I'm not skilled enough to have made the mask with a perfect right angle so I could simply butt it up against the edge of the scanner glass for correct horizontal orientation, so getting negatives perfectly aligned to the horizon can be tricky.
A crude jury rig? Yes. But with careful fiddling, it works okay a lot of the time. Here are examples, 2400dpi scans of Double-X negs from my Pen F and Pen S: