Even with good and sufficient agitation, I expect and find variations in the development of my negatives when comparing beginning of roll to end of roll.
I also expect and find variations in development between the center of a strip of film and nearer the edges even though there aren't visible surge marks.
These differences are measurable with a densitometer, but I am happy to say that they don't ruin prints.
If you'd like I can show some numbers.
But the important thing I want to say is that agitation is important, difficult to get perfect, but not too hard to get just right.