You just get more light scatter with larger enlargements, so bigger prints often need to be printed at a little higher contrast than smaller prints.
If you have a good contact sheet, with some experience, you should be able to make one good print, and then use the contact sheet to determine your approximate exposure time and contrast grade for subsequent prints based on the exposure and contrast of the first print and by looking at the contact sheet. Meaning, you shouldn't have to make a test strip for every print, but you still might want to tweak every print based on your first attempt. How much you tweak depends on what your goals are.