My Vuescan runs great on machines that started out as Windows 10, and on a machine that started out on Windows 7 and whose operating system was upgraded to Windows 10.
I'm guessing, but I wonder if the "high end Windows 10 machine (he/she/they) built" has a super special video card that Vuescan and Silverfast have trouble with.
"high end" often means a gamer's machine with really fast video capabilities.
My scanning / editing machine is also my gaming rig-- Admittedly, it's a bit old now, but it's a Ryzen 7 1800X, with 32GB DDR4-3200 RAM, and an NVidia GTX 1070 Ti video card. I don't do version to version upgrades, so it was clean-built as windows 10, and my old profile was migrated over via the "User State Migration Tool" (since Microsoft deprecated the Windows Easy Transfer utility).
I assure you-- the speed of the graphics card has nothing to do with how Silverfast, or Vuescan, perform. I don't even think they're touching the directX libraries, except for indirectly by creating windows on the desktop.
However, especially for boxes like mine (X370 chipset), the USB 3.0 drivers are a little persnickety, so it's always worth putting your scanner into a USB 2.0 port, and it's definitely worthwhile to download the official drivers for all of your USB chips. In the case of my motherboard, the USB 3.x driver is by one manufacturer, and the USB 2.x drivers are by a different one. That's not the fault of the OS-- it's the fault of the hardware.