Thanks for all the answers so far.
I am currently duel booting Mac OSX and Linux, and using Vuescan for my mac. The issue I had was that darktable, my preferred editing software, seems really buggy on a Mac, but works perfectly on Linux. For example, it crashes when I have folders with Jpegs and Tiffs in it.
For now, I am scanning on my mac and then transferring the files to linux. It works, but is mildly annoying. I hadn't thought of WINE, but I will give it a shot.
The plustek issue is seriously annoying. I really like the scanner and it produces great results, but why no linux version? how difficult can it be?
I was thinking of going to a flatbed so that I can scan 120, but the quality of the plustek dedicated 35mm is so good I feel I might lose something, and the vast majority of what I do is in 35mm. If I buy a flatbed to add to the 35mm scanner my wife might murder me.