I think it depends on the case -- at least to some extent. I have a lot of cases, but two favorites, and one reason why is because of the way I can arrange cameras in them. In these two case's examples, I can insert the camera into the bag with both motor drive and short to medium length tele or zoom attached. But in the other end of the bag, I can insert a camera body with motor, but only if it doesn't have a lens attached. Or I can have both cameras with lenses attached as long as both lenses are short ones, say 100mm or shorter. Plus the bags are roomy enough where I can still store at least four more lenses in their own padded pockets. So how often I'll be swapping lenses will depend entirely upon the variety of shooting I'll be doing. I always assume that I'll be swapping lenses when I'm out in the field, so this is just something I think of as part of the routine. And talk about tedium -- at least half the time I'm out with film gear, I'm packing Canon FD cameras and lenses, and most of my FD lenses are the older breechlock lenses, which are infamous for their tedious, fiddly nature when it comes time to swap them out. But it's just something I've gotten used to. If I want to bring my Canon gear out to play, I know I'm gonna have to deal with it, that's all.