I run Advanced System Care
https://www.iobit.com/en/advancedsystemcarefree.php and occasionally CCleaner
https://www.ccleaner.com/ Microsoft calls them "snake oil" but they help.
Windows has some builtin utilities that fix problems that cause programs such as Epson scan not to run properly. They are System File checker and Deployment Image and Maintenance Tool. They are run from the command line of Administrator Command Prompt.
The syntax is:
sfc /scannow
and
DISM.exe /Online /Cleanup-image /Restorehealth
run sfc up to 3 times in succession to fix problems then dism.
These can be verified on microsofts support site.
The problem you are experiencing is in Windows not epsonscan.
The easiest way to get an administrator command prompt is to right click the start button.
Will not harm your computer, will likely fix it.
The latest Windows system upgrade installed correctly on 2 of my 3 computers but the 3rd I had to manually delete the update files and redownload them.