- You won't get scans that are perfectly sharp edge-to-edge unless you use a glass carrier in either the Epson or the Nikon
- The ability to focus the Nikon sets it way ahead of the Epson in terms of usability in my opinion.
- I have both an Epson V700 and a Nikon 9000. I can get reasonably good medium format scans on the Epson, but it's far easier on the Nikon.
- I use VueScan on Windows 7 to drive the Nikon and it works well.
- If you want to scan smaller formats, the Nikon is a better choice than the Epson
- I would be without the Epson -- I use if for making contact sheets, scanning prints, OCR, and other odd jobs that require a general purpose flatbed
Judging by the performance of my Nikon Coolscan V compared to my Epson flatbed I would say you were in with a good chance of getting a winner! The Nikon 9000 was the Crown Prince of Scanners!
Even though the Nikon scanner is quite old by digital standards, it has superb internal workings that are 2nd to non. The Digital Ice software is far superia to that on a flatbed and will get rid of quite difficult marks without a great deal of fuss. The D max is if I remember 4.3, when flatbed scanners struggle to get to 4. There is no glass plate to atract dust and the film is held perfectly flat. Even so there is an auto focus feature that ensures this. Scans at high resolution are not exactly speedy, but who wants to hurry quality?
The main drawback is if you use the original Nikon software then it won't work with any later Windows than XP. You can get hold of Silverfast software which will get things moving again, but I am not so sure if you retain all the facilities if the scanner. I have also heard that sometimes it is awkward to get the Silverfast to work properly. I get around this by using an XP laptop with my scanner and saving the scans onto a memory stick. Then transfering the memory stick onto my PC and use Photoshop for any afterwork.
One advantage of the Nikon scanner is you can scan negatives or transparencies into RAW files. Ordinary Adobe RAW will take care of them. BIT depth is either 8 or 12 and with 35mm negatives in NEF (RAW) scanned at 4000DPI my files are well over 120MB each, so think of the available information that is recorded even off 35mm.