Yes, it's perfectly straightforward, I've done it . You might find some rather weird colour shifts of course or other oddities, problems with contrast, density etc.
You can either follow an E6 type process (using E6 chemicals) or you can process them using C41 chemicals (using an E6 procedure - i.e. first developer then bleach then fog then process as normal) or as black and white reversals. In the latter two cases you'll need a separate bleach (if you use a blix after 1st dev it'll nix te reversal process
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There#s loads of threads here on this sort of thing, which is where I picked up most of the info I needed to try it. For how to do black & white reversals have a look on Ilford's site, there's a detailed how-to PDF you can download