I'm running an older UMAX Powerlook 2100XL under Win XP. I just bought a cheap PCI SCSI card, installed it and the drivers and it worked without hassle.
Look for an Adaptec SCSI 1 card if you have a 50 pin cable, SCSI 2 if your cabke supports 64 pin. Ebay has a lot of good deals on SCSI cards. Windows XP will probably recognize it automatically.