The refugee photo is so highly manipulated that it obviously represents photo commentary, not photojournalism. To me, it looks more like a staged painting than a real photograph.
The drug addict photo appears dark. Since there is a plain shadow in the photo, it appears that the photograph was intentionally darkened. Did this occur when it was taken, or in photoshop, and does it really make a difference?
Neither of these images bother me because neither represents news where the details of the images are needed in order to represent facts. Both of theses images were manipulated to convey emotion, not to change factual events.
Framing and composition can give false facts just a easily as photoshop. There was a recent photo of a refugee child wandering through the desert, separated from his family. Another image taken at the same time demonstrated that he was separated from his family by 30 feet. Both photographs were real, but composition and framing gave completely different representations of reality.
The best safeguard we have in the developed world, is that many events are photographed by multiple photographers and obvious manipulation will be brought to light.