I've been painting for decades and I haven't once thought that any paint brush felt bad enough in my hands to impact my art. I've never heard any of my fellow artists complain of that either. In fact, we'll quite often use tiny nubs of charcoal that hurt to hold because that's the first one we grab, and it's more important to us to draw while the inspiration is there, than to dig through a drawer looking for the perfect stick to hold. We may complain about the bristles being too stiff, frayed, or fragile. We may snap a brush out of frustration because the tip won't hold a point anymore. But I don't think I've ever heard anyone complain about the weight, balance, or tactile feel of a brush. All that matters is how the canvas looks. Pain is art. You have to embrace it if you want to be an artist, because that's where the good stuff resides.
Same with musical instruments. The novices and weekend warriors love instruments that play smoothly. But professionals don't usually care about that. They usually want instruments that sound great, and the feel and look of it are all secondary. Jack White is known for saying he hates guitars that feel good in his hands. He likes to fight with the instrument. He says it gives him a better connection with it. Same thing with most violinists. Your typical Stradivarius is usually a devil to play. They are hundreds of years old and frequently have warped and worn out fingerboards with twisted necks. A cheap, modern, Chinese made student violin is typically easier to play, but they don't sound anywhere near as good. Or what about Dizzy Gillespie's famous trumpet? He had them manufactured with the bent bell, which made them harder to play, but he liked the unique tone that the bend gave them.