A few recent examples, all shot handheld.
1/1000s, f/8, with flash
1/1000s, f/8, with flash
1/80s, f/7.1, no flash
1/1000s, f/22, with flash
These few pictures to illustrate 2 things for whoever has not tried close-ups / macro photos:
- the depth of field is really so tiny that capturing exactly the part you want when handheld is hard, and additional light (to decrease the aperture/increase the f/ number) is always welcome;
- whether manual- or auto-focus (there are both here.. guess which ones), it is more about having the focus point right where you want, whether that is adjusted by AF or by setting up focus and moving slightly to adjust that focus point.
If the object of the photograph is not moving and the pictures are shot inside, a good macro stand with strong lights and focus bracketing should be your friends..