My PC is off line so I can only respond through iPhone here.
Every time I’ve had this occur I had to use compressed air, very carefully, in the scanner bay area to blow light dust off the scanning element. It has fixed the issue for me several times over many years. Once I performed this as a last thought the first time I encountered the issue the very next scan was clean.
That is almost assuredly a dirty mirror in your scanner. To make sure, flip the frame upside down and scan again. If the line is exactly the same, then it is the lab. 99% it is probably your scanner. If your scanner has a calibrate function, you should use that too. You should actually always use that before you make any scans.
I see this often enougn. Chemical (surface) residue on the film, particularly from labs using roller transport rather than dip-n-dunk. Clone it out (along with the blue line) in PSP/LRM (along with the heaps and heaps of dust!) and evening-out of corners (vignetting). Film can also very easily be scratched in-camera (just a speck of dust or dirt over the gate is enough to cause a lot of damage). "Odd green crystals" can also be symptomatic of excessive humidity, of which all Velvia emulsions are sensitive to.
Leave Digital ICE off for colour scanning — it is much better to master dust-removal by clone-out with tools.
I'm using a different scanner (Minolta Dimage Scan Dual III) and occasionally get a faint line at the edge of the long side of the scan. It's not on the film and goes away if I recalibrate the scanner. I use Vuescan and it's an option in a menu. Epson scan might not have it.I will try this and report back. I don't know where the mirror is though. I don't think the scanner has a calibrate function -nothing about it in the instructions.
I'm using a different scanner (Minolta Dimage Scan Dual III) and occasionally get a faint line at the edge of the long side of the scan. It's not on the film and goes away if I recalibrate the scanner. I use Vuescan and it's an option in a menu. Epson scan might not have it.
Best of luck.
. I would also almost certainly introduce more dust than there is already.
Yes, that's right! Scanners are assembled in a clean environment. Opening them up will only make the problem worse, beside the placebo effect.
Dust and discolouration annoyed me so much I put my Epson V700 scanner out for kerbside recycling, as all of my photographs are drum-scanned (Heidelberg). I don't miss it.
Transparency film will always attract dust, so will mono film. A wipe down with an antistatic cloth is god pre-prep be free scanning, but should not be done on thinner negatives.
So you have your films scanned by the lab? I have considered that but high resolution scans are expensive.
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