The difference between having a mirror and having no mirror is not readily quantifiable in general terms and the difference between an SLR and rangefinder in use is more about whether the particular camera model is a good match to the individual photographer and the job at hand. David Goldfarb's point about the wider parameters and greater ease of designing wide angle lenses without compensating for a mirror's physical requirements is well taken, but in practice there are good and bad wide angles among both rangefinder and SLR optics.
I have a very solid brass-bodied SLR with a cam driven mirror. With the mass of the body and the deceleration of the cam drive mirror (to the point that it really doesn't slap against the rest of the body at the top of the cycle), it does very well at pretty much any shutter speed. I have been repeatedly surprised over the 30 years that I've used it at the degree to which I can handhold at slower shutter speeds.
I have an Argus C3, an Agfa Isolette folder, and a Bessa R3A, all rangefinders. The difference in their viewfinders is more significant a difference in practice than between say the R3A and a nice SLR finder.
One other thing that I find more significant than mirror slap in the cameras I've used is whether the camera fits my hands well. I have larger hands, and even many SLR bodies aren't large enough for me to get a good grip. The Nikon N8008s body is short and thick, and the bottom of the body doesn't even reach halfway across my right palm with my finger on the release button. I don't feel that I can hold it very steadily. Bad ergonomics for me personally. I put a trigger winder on my C/V Bessa rangefinder bodies to make them fit my hands well, and they work great for me that way.
There's a lot more at play than a simple mirror/no mirror question if "sharper negs" is the goal, and in many (perhaps most) circumstances, I think that gets swamped by other considerations, including individual camera build, individual lens quality, overall ergonomics of the particular camera model in your hands, your overall comfort level with the given camera, and your individual skills/ability to hand hold steadily.
Lee