It depends. For one thing, how deep your pockets are.
Printing paper (especially FB) is no longer as cheap as it was. For many years when Kodabromide, Kodabrome, Polycontrast and eventually Multigrade in avatars III and IV didn't cost the price of a kidney, I printed like a mad fiend, endured long (as in "all night") printing sessions and often as not threw out as much printed and processed paper as I kept finished prints.
Eventually I realised I was wasting more good paper than I kept and I decided it had to top. Fortunately, good photo scanners then came on the market. Scanning has freed me from the tyranny of the darkroom. No more all-night printing sessions and lost sleep. Or waste baskets filled with expensive unwanted prints. True freedom, this.
I never, ever print 11x14" as I long ago gave up boring friends and family with showing big prints. These days when I (infrequently) set up my home darkroom and print, I make nothing bigger than 5x7" which to me is the ideal size for 99% of my 35mm negs. Or square prints on 5x8" (8x10" sheets cut in two) for my Rollei negatives. an 8x10" from my darkroom is a rare event, in fact making an eight-ten nowadays rates a glass of good red wine.
What really saved my sanity was a fortunate find in a secondhand shop - a Patterson test printer. I paid as I recall, A$10 for it and it has simplified my test strip making. A 4x5" sheet cut in two gives me a perfectly adequate test prints. I can then fine-tune the rest of my enlargement and often as not get it 90% right, which is good enough for me, with the first print I make.
I now scan all my good images as tests, which lets me visually inspect the scenes and work out what I want in a final print.
It's also entirely true as you say, perfect negatives don't exist, never did and never will. But good negatives can be made better. I improved all my images when I finally forced myself to stop taking pretty landscapes and included less sky in my images. Also I no longer shoot very much on bright sunny days and concentrated on more overcast day situations. This works for me.
All this worked for me and it may for you. Tinker with things a bit and fine-tune your shooting and printing. Lateral thinking can be fun.