If it's connecting in the bottom of the crawl space, with tub (and presumably toilet) above, I would think you would want that vented. You could try it without and see if plumbing drains well but I would use one of vents I mentioned (I looked and they're call "cheater vents" or "check vent").
I'm guessing they're the same as what Steve Smith called "air admittance vents".
Thanks for the info you guys, I appreciate it. I will keep the "check vent" in mind when I get a plumber here------tomorrow, I hope to get the sink itself made, will be an 8 foot bottom and 32" wide as I hoping to accomodate some 16 x 20 printing some day, but mostly it will be 8x10 and 11x14.