For C41 and E6 processing, there is an advantage to a separate bleach and fix. The bleach must be very strong in order to remove all of the silver. If it is not, then grain increases and color quality decreases. Also, the blix shelf life is very short.
As photo engineer states, separate bleach and fix is preferred. The coupled dyes produced in the (colour) developer continue to build in EDTA bleach.
When bleach and fix are mixed, this effect is slowed and storage becomes a problem. The mixture oxidises and the two components begin to react together. By the time sulphur begins to precipitate, the solution is useless. On its own, brown EDTA bleach has a virtually indefinite lifespan but, paradoxically, must be aerated before use (shake the half-empty container for a few minutes). Note that the process instructions assume that the bleach and fix will be used at 38°C - immerse for at least twice as long at 20°C.
C-41 and E-6 fix have a lifespan similar to B&W fix. Although they are chemically similar, C-41 and E-6 bleach and fix should not be swapped.
For stable negatives and slides, use the appropriate final bath or stabilizer in the recommended procedure. Avoid frothing and leave to drip dry - do not squeegee.
I have Ektachrome transparencies processed by hand in E-6 chemistry from about 1978. They were mounted in glass. I bought a 1958 6x6cm slide projector a month ago and the images are still excellent.