Michael - Interstate 80 is the fastest way to get across the full width of Nevada; but otherwise, it's a boring freeway. There are places nearby that are wonderful to visit, like the mountains above Elko. But I prefer Hwy 50 for its relative loneliness, as well as the nearly empty north/south paved connector roads between 50 and 80. Do you want to see wild horses or semi-trucks? Nevada is a gorgeous State from the air. But even what seem to be long stretches of monotonous sagebrush can suddenly change to sheer magic once clouds or snow are involved. Yes, when crossing Nevada, I'm using either going to or coming from someplace else. But I always save extra time to explore Nevada, at least in one of those directions. One of my old routines was to stop at little local breakfast spots and start up a chat with the locals - they tell you about all kinds of special places (unless you're a hippie, and then they lynch you instead). Then on a later trip I'll go to some of those places and spend quality time there. Most of the State is actually dirt roads; but you don't want to get stuck way out somewhere, way out of cell phone reach.
And yes, TMax is a wonderful film for the high contrast scenes likely to be encountered on such a trip. Except when forest fire smoke drifts across from California, the dry air in Nevada tends to be very crisp, even harsh.