It does appear to be from cleaning, either incompletely or residue from a liquid cleaner. Doubtful that it will affect image quality in a noticeable way except perhaps at the widest aperture. It shouldn’t be difficult to clean with a coated lens cleaning solution and a fine lens cloth or tissue. Add the solution to the cloth, not the lens, and wipe the element in an outward circular motion. Given that the smudge is on the edge, you may only need to clean the outside of the element. Smudges like that can happen when the grease from a fingerprint is not removed completely.