My take is that you find the tools that work for you, and that allow you to express your vision, and work with them until they are honed and their use becomes second nature. To some (myself included) this has been at quite some cost along the way to find the right outfit that works for you. Be it large format, a Hasselblad, a Holga, a pinhole camera, adapting a funky lens to a camera, or whatever you use to demonstrate your vision. Familiarity, and knowing what its capable of and learning to truly see are where successful images are made.
I took a workshop with Fay Godwin back in the UK during the early 90's. After seeing her low-tech approach and sticking with familiar 'tools' so that nothing gets in the way was drummed home to me. It changed how I viewed image making forever. I only use one or two films and one developer anymore...... Simplicity and knowing how to use all the tools together is key.
If you have too many choices though, it just gets in the way.