About a year ago there was a documentary broadcasted here in the Netherlands that showed how probably many renaissance painter used a camera obsura to create their masterpieces: 'evidence' as artifacts in paintings due to refocussing (a hand that doesn't fit quite right to the arm), looming of shapes, left-right mix-up when a mirror was used (too many lefthanded people in the painting), fine/complicated details that 'escaped' the painters in earlier years but are present now.
One can never be shure, but it was very convincing.
Huib