Yes, but even so, I'd expect the difference to be so marginal as to make the option of re-scanning not very relevant. I'd not bother unless you are seeing severe problems in your scans, which I bet you're not experiencing.Might it matter that the ScanMate is a drum scanner?
Do a check. Scan the same negative twice, both ways (emulsion in, emulsion out) and compare. That will give you the answer.
Easier said than done when negatives are already mounted on the drum. Mounting fluid, mylar and all...
Wouldn't you get moire patterns if the film is against the glass?
That's pretty compelling. In the sense that I really don't see much of a difference at all.But, if OP can't do a comparison, somebody else surely can...
@brbo - what scanner are you using?
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