I learned to scan on a Microtek 8700 Pro with Silverfast AI 6. I'm not that experienced with HDR scanning.
Try setting the Negafix to the film you are scanning, set the black and white points with all other controls at their neutral position, then make a standard test scan then make additional scans adjusting the exposure setting in 1/2 stop increments each side of the start point up to the point you get noticeable degradation in the image then compare the scans to see what gives you the best result.
It took me 18 hours to learn Silverfast spread out over 3 or 4 days. I started with a good negative, made a software auto base scan for reference, started adjusting one variable at a time making a scan for each adjustment until degradation showed then two variables at a time then three at a time until the limits of each individually and in conjunction with others was reached. I used a 1200 dpi resolution to limit scan time then checked the results in PS.
HDR scanning will require some work also to get the optimal results, online tutorial is a good start point.
You will find that most correctly exposed negatives scan well with one setting but an occasional one will require extra work.