The advantage of reversing the lens when shooting above 1:1? Well, a lens can be optimized for only one magnification. Most taking lenses are optimized for 1:20 or smaller. By reversing a lens when shooting it above 1:1 we take better advantage of its optimization than if we use it above 1:1 facing normally. Clearer?
The only lenses that don't need to be reversed when used above 1:1 are truly symmetrical. There aren't many, the Apo Ronar line is an example. So are dialyte type Apo Nikkors and Apo Saphirs. Some Apo Nikkors are tessar types.
As a practical matter, the gains above 1:1 from reversing the lens depend on the lens. In general, fast lenses do worse facing normally above 1:1 than slow ones. Really asymmetrical lenses, e.g., tessar types and retrofocus lenses and telephoto lenses, do much worse than more or less symmetrical ones, e.g., plasmat types and slow double Gauss types. I don't have what you do, so can't do the right experiment for you. But you have your lenses and can ask them. Ask them!
Also, as a practical matter there are a few lenses that somehow manage the impossible. For example, I have a 100/6.3 Neupolar that shoots very well facing normally from around 1:8 to 8:1. It is a reversed tessar, i.e., a tessar with the cemented doublet facing the subject. And when I can focus it, it is spectacular at distance but doesn't have much coverage.
You are mistaken re DoF. I just did the calculation. At 1:2 and f/x and the same CoC a 90 and a 165 have the same DoF. The 165 has more working distance, that's all. Try the experiment. I once did it with the same subject, illumination, and emulsion. At f/8, KM transparencies of the same subject shot at 1:4 with flash and a 55/2.8 MicroNikkor AIS, 105/2.8 MicroNikkor AIS, and Questar 700 were indistinguishable. Equally sharp, same DoF, i.e., not much but the same in all three. The Questar 700 is a 700/8 (nominal, actually T/11) mirror lens, highest magnification 1:4.