I just got back from a week in Santa Fe/Taos. Here is what I brought on board:
In my Tenba backpack:
Dell Laptop, 10 hour battery, lots of cables, Gaoersi 4x5, 47mm-150mm Zoom Finder, 75mm Grandagon N + shift mount adapter, 47mm XL + mounting adapter, Polaroid pack film back. Horseman 6x9 back, Horseman 6x12 back, Schneider 8x loupe, Laser rangefinder.
In a "normal" carry-on bag w/ wheels:
Mamiya 7II + 50mm/finder + 80mm + 150mm + macro lens + LowePro should bag. 40 rolls of Kodak 400NC in lead pouch, BetterLight 4x5 insert + battery + hard drive/controller + cables + lots of bubble wrap
I had no problems whatsoever other than some quizzical looks from the TSA dudes at all the equipment.
For me the moral of the story is: look like a professional and they treat you like one.