I have little experience with C41, lots with E6.
For commercial work, I rarely ran film straight - usually a 1/3 or 1/2 push. This always seemed to pop the contrast a hair and brighten teeth and eyes subtly.
When pushed a stop or more, you'll start to really close up your shadows, which can look dramatic, or bad. We would always have the lab run snip tests - 8" or so of the head or tail, and judge the rest of the roll from those.
BUT - this was shooting in controlled situations, studio or location with scrims, flags, reflectors. So usually not dealing with harsh light. And you needed to do tests to see how a given film reacted since color accuracy was key in most gigs other than pure editorial stuff.
I really, really got into pushing Kodak's 320T film (EPJ, Tungsten) two to three stops (I often shot it at 1600 or higher) and then duping those 35mm slides onto Velvia with an enlarger and a flash head taped into the condenser box (DIY daylight enlarger). Amazing color saturation and pastel-like grain - shadows could be controlled with fill light.