We have printed 60 x 90 cm glossies from a 35mm negative scanned with a Nikon Coolscan LS 5000. One subcontractor delivered fantastic results, three others ended up in the trash can.
If you have access to the printer and can calibrate it so that it meets your requirements, you can push the envelope a lot.
Blowing up (or resampling) a digital image from a Canon 20D tends to turn flat and unsharp at anything larger than A4 or double letter size.
I'm currently thinking to get a Coolscan LS 9000 for my 6x9 slides because the Canon 9950F definitely does have a limit @ 2.400 dpi. The 60x90 cm prints are not bad, but they could be crisper, and because I'm a freak when it comes to perfection I don't see an alternative.
I was thinking to invest into the new Fuji S5 Pro because I could use all my Nikon lenses with it, but as great as the images are, they are too small for my purposes. IMHO digital cameras are good stuff for letter size prints, but that's about it.
My biz partner is shooting digital and has to spend hours with Photoshop, but I prefer perfect slides, a nice scan and a click to print