Yes, there are lots of ways to skin that cat, but in the end, it all comes down to how it applies to your need at hand.
If you want to interpret the data within classic sensitometric/densitometric methods, I don't think it can be done.
If you want to take the characteristic curve generated by multiple identical exposures of a negative processed at differing compaction and expansion times out of formal sensitometeric interpretation, sliding the curves up and down, left and right (but NEVER rotating them), forcing all curves to intersect on a particular Zone, then you CAN make the curves cross each other, slight as it may be, without changing exposure, and you can get some useful information from that exercise.
You are essentially changing the dynamic range and gamma of the filmstock with compaction and contraction, but the amount of slewing around the fulcrum is going to depend heavily on how radically you alter your processing from "normal" (actual gamma), where you put your aim point on the curve (usually within the straighline portion) AND where the majority of the information falls on the straight line portion of the negative (apparent contrast) within the dynamic range of the emulsion.
Come to think of it, I don't know if that description is actually valid, because I am attempting to describe an event using descriptors that depend on a rigid implementation of a process that we just threw out the window, if you see what I mean!
Precision densitometry and sensitometry required to make this a science, lends itself more to machine-based processing than tank/tray processing (yes, there are many out there who are remarkably consistent, no doubt) because of generally uniform, batch to batch results.
When you mix a certain developer in 50 gallon batches and have a 150 gallon tank from which you replenish a 500 gallon, well-seasoned developer, and run and plot control strips 4 times a day, you tend to fairly consistent results that can be tweaked fairly tightly to a certain process gamma.
However, even this process has "wobble" and acceptable limits of variation, so you can imagine how relatively useless it probably would be to try to run this sort of system daily in your darkroom for quality control if you operate on well seasoned intuition!
That's not to say that this sort of information cannot be useful to home lab users; it can be, but I would imagine it would be only in a very general, comparative sort of way; a jumping-off point from which to fine tune your experience base.
Shoot two identical negs, soup them in a known developer and an unknown developer, measure identical patches and compare densities; "oh, it's a stop more dense, I gotta remember to back off a stop when I want to develop this stock in this developer"'; that sort of thing.
To be stupidly obvious, I think art photographers have a very sophisticated internal database, for lack of a better term, that is called "experience" and from which flows intuition. I also think it follows the same rules of classical sensitometry, but not it a manner that sensitometric language would approve!
If you were a photolab that needed to nail this process down for repeatability, you would invest heavily in testing and documenting this process to ensure repeatability.
As a art photographer, you may do the same, but have much more room to experiment a fine tune on a case by case basis.
I'll shut up now...