If you want to shoot it manually you can
If you want to shoot it like a 1970s centreweighted camera you can
If you want to shoot it spotmeter you can
If you want to shoot it with the most modern metering system you can
You can put every lens nikon ever made on it (i think this is true of f6 - there are no exceptions like with other nikons)
To me it looks utterly brutal. Use it any way you want with anything you want.
But you have to drag the fucker around anyway. The electronics comes at the price of weight and one more thing that can run out apart from film.
I’m not saying the F6 or any of nikons high end AF cameras are worthless, they certainly have their place.
I just think it’s a matter of people lusting after it for the wrong reasons, and then not wanting to admit they where wrong when they do get it.
A frame shot on the same film in the overwhelming amount of cases will look indistinguishable, whether it was shot on a 1959 F or a 2019 F6.