I've used several Sigma lenses with an F100. The Sigma 35mm f/1.4 Art works fine on an F100 -- but some of their lenses use electronic aperture control and can only be used wide open on an F100.
Did you need to do any kind of calibration, and if so how did you do it on the f100?
As for AF Tuning, if you get the dock I believe you can tweak AF with even more control than Nikon offers for its own lenses on dSLR's, although you can burn through a fair amount of film trying to get it just right.