Just to reply to you ...
With my Coolscan using Vuescan I am using medium for the infra-red setting (Digital ICE) and medium for noise reduction or maybe it's called reduce grain. With Nikon Scan I turn on Digital ICE (Normal) and I set GEM to 1.
Slide film and Ultra Color 100 is a bit of pepper grain but not offensive.
With my Coolscan I find that with C41 I need to use Digital ICE b/c it picks up so much dust spots etc .. even if I turn it off and just use GEM I at times get white speckles on the scan.
I have tried using Neat Image, to me does a similar job with more minor adjustments but when I put it thru auto ... it really really makes my image like a cartoon
My question was how do you guys scan C41 given the amount of noise the Coolscan picks up? Also that more so in the past wedding/portrait professional photographer used these 160 portrait film and clients wanted enlargements. Does anyone know how they made prints? What was the process like - did they enable noise reduction and print it off a Frontier system or have hand prints done? I read about hand prints but not sure what that really is, never used them myself.