I prefer Vuescan, not because it's a much better software (actually it is - but it is a little more complex / cumbersome than Epson OEM at the same time. Anyway, that isn't the primary reason to me, see the following ->), but because I can use it for all of my scanners (Epson 2450 + Minolta Dimage Dual Scan III), and it works in all of the operating systems I run. (Windows 7 64bit, Mac OS X 10.6 and Ubuntu Linux 10.10) It seems I like stability and consistency very much!