I really like my F-Stop Loka, but unfortunately affordable is not a word that belongs alongside F-Stop backpacks...
While the bag was expensive (as was my Hadley Pro), my thought was if I'm going to be using this bag for x years/decades (the Hadley is 10 years old, F-Stop I bought used 3 years ago) and taking it around town all the time, hiking on every trip, then I don't mind paying more if it get me out shooting in comfort more.
If you have a chance, go to a camera store and try on these bags, and see what works well for your style. You may decide you want a pack you can access without putting the bag down (such as the Lowepro example) or you may decide you don't care. You also might want something with a better suspension given the weight of MF gear. My old Lowepro Rover AWII was still able to fit my Hasselblad along with the extra lenses I bought (I previously had a small kit--just an 80mm and a spare back), but it wasn't all that convenient, and it wasn't comfortable with all that weight on just my shoulders, which is why I bought the F-Stop.