I've run some tests on the 65, I have a Sekor C. I focussed on a test chart at 1 m away, then set the lens to floating element to infinity, took a shot, then set the floating element to 1m, and took another. I couldn't see any difference between the transparencies to be honest, edge sharpness looked the same to me, even under a powerful hand lens. So on balance I would say that it makes little difference. The non-c lenses are single coated rather than multi-coated, so flare may be more of an issue, but get a good lens hood and that should sort it out. The lens hood for the 65mm is the same as the 50mm, and it could really be a lot deeper and still avoid vignetting the lens on the 65, so I tend to use a different shade. The mamiya bellows ones are probably very good, but I use a Lee standard bellows lens hood that works great. I try to use a hood on my 65mm as much as possible as it has quite a few cleaning marks that could flare in strong light.