What chemicals are you planning on using? I'm assuming no pyro developers, or toners.
If you are using standard black and white chemicals to develop and print, just clean the tub and surround before and after darkroom use.
The cleaners you use to maintain and clean the tub and surround are probably of greater concern than the darkroom chemicals.
I nest the trays I use in larger trays to minimize spillage, but that is mostly done to make cleanup quick.
A hand-held shower spray also makes it easier.
This will give you a sense of what I do for printing - the top 11x14 inside 12x16 tray is the fixer tray - the stop bath and developer trays are to the right on the top shelf.
The two wash trays - one draining into the other - are below:
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