I've only shot one roll of Efke 100, and it was in 35mm. IIRC, I developed it in D-76 1:1, but I'm not positive of that -- I might have used XTOL 1:1. The negatives, though, were very grainy -- grainier than most ISO 400 films, in my judgment. I don't know if anything could be done to significantly reduce the grain, although switching from Rodinal to a fine-grain developer might give you some modest improvement.
Efke 25, OTOH, is a very fine-grained film. I haven't shot enough of either to know how they compare in other characteristics, but if you like the Efke 100 other than grain, you might give the 25 a try, or perhaps the 50 if losing two stops of speed is too high a price.