The answer is "whatever works for what you see in your head"… digging through my portfolio, these were all shots where I had a very specific feel in mind and was able to translate it to film or digital - I really don't think "simple or complex", I think about what I want to see and if I want it to look real or very-not-real-at-all:
1 soft light, very simple, polagraph film:
Really insanely complicated, Ektachrome 320T, no retouch, probably surrounded with a dozen light stands, 2 layers of glass sheets, etc:
Fairly complicated, strobes with full CTO and tungsten fresnels, 320t as well:
Kinda complicated, shot in a very busy nightclub, CTO-strobe clamped to ceiling, tungsten BG: