I've found that when doing 4x5's they acctually need more agitation than the 35mm. I'm guessing, due to your explanation of how you agitate, that your using the deep tank system. if so, try using a little more agitation. The artifacts are most likely from that, as many have said. And if you want a lower contrast, you might consider cutting down development (only a little), and using a grade 1 paper or VC filter when at the enlarger. Personally, i try to get pretty dense negatives, and lower the contrast at the enlarger if i desire. But that's just me. Anyways, good luck. Im excited to see the outcome.