When I went condo shopping sometime back, one of the deal-breakers was that the property must have two bathrooms. My agent thought it an odd request... Why would a single person would want - or even need - two bathrooms. Then I explained my intention of using the second as a "semi-permanent" darkroom. She understood. "Semi-permanent?" Well, those of us who have the good fortune of living out here on the coast, have noticed that we seem to have lot of guests during the winter months, generally folks looking to escape the bitter, soul-destroying cold of a Canadian prairie winter. I generally leave my darkroom set up on a full time basis, and soup and print at my leisure. When folks arrive, the enlarger, timer, trays, tanks, etc. are carefully packed into a hall closet - an effort that takes maybe 20 minutes.
The location of my darkroom/bathroom (off the hall, one room down from my guest bedroom) is such that drawing the living room drapes, turning out the kitchen and hall lights, and placing a dark colored towel over the bottom of the door achieve sufficient darkness. My only real "modifications" are a piece of black velvet (about two meters long) duct taped to the ends of a track light which runs the length of the vanity, unscrewing the bulbs of the track lights, and replacing one of the track lights with the obligatory darkroom red. Despite being dual-purposed, I have had no issues re fogging, chemical stains, etc.